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Last Updated: Oct 22, 2026

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BPS BPS-Pharmacotherapy Exam Syllabus Topics:

SectionObjectives
Topic 1: Disease State Management- Endocrine and metabolic disorders
  • 1. Diabetes management
    • 2. Thyroid and lipid disorders
      - Cardiovascular disorders
      • 1. Acute coronary syndromes
        • 2. Hypertension and heart failure
          - Infectious diseases
          • 1. Antimicrobial therapy selection
            • 2. Resistance management principles
              Topic 2: Part II: Applied Clinical Decision Making- Case-based pharmacotherapy scenarios
              • 1. Therapeutic optimization in multi-morbidity
                • 2. Complex patient management cases
                  Topic 3: Part I: Knowledge-Based Assessment- Foundational pharmacotherapy knowledge
                  • 1. Guideline-based treatment approaches
                    • 2. Drug mechanisms and clinical use
                      Topic 4: Special Populations- Renal and hepatic impairment
                      • 1. Dose adjustment strategies
                        - Pediatrics and geriatrics
                        • 1. Age-specific pharmacotherapy considerations
                          Topic 5: Patient Care and Pharmacotherapy Principles- Medication management
                          • 1. Adverse drug reaction management
                            • 2. Dosing optimization and adjustments
                              - Therapeutic decision making
                              • 1. Drug selection and individualized therapy
                                • 2. Evidence-based medicine application

                                  BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

                                  Question #1

                                  A MEDLINE search fails to retrieve a clinical trial known by the searcher to have been published in a recently established open-access medical journal. This failure has most likely occurred because of which of the following?

                                  • A. The searcher limited the search to "humans" and "English language."
                                  • B. MEDLINE selectively indexes articles of the highest scientific merit.
                                  • C. The time that the journal has been available does not meet criteria for indexing.
                                  • D. MEDLINE does not index open-access journals.
                                  Reveal Solution  Discussion  0

                                  Correct Answer: C  🗳️

                                  Question #2

                                  A pharmacotherapy specialist wishes to investigate the impact of thiazolidinedione therapy on Weight gain. The specialist will determine average body weight immediately before participants begin therapy with pioglitazone and again after they complete 12 weeks of treatment. Which of the following statistical methods is most appropriate for analyzing these data?

                                  • A. Fisher's exact test
                                  • B. Paired t test
                                  • C. Chi-square test
                                  • D. Unpaired t test
                                  Reveal Solution  Discussion  0

                                  Correct Answer: D  🗳️

                                  Question #3

                                  For a 34-year-old Woman with a history of ethanol abuse, cirrhosis, ascites, and jaundice, which of the following is the most important factor predisposing her to hepatorenal syndrome?

                                  • A. Hypokalemia
                                  • B. Metabolic acidosis
                                  • C. Volume depletion
                                  • D. Hypocalcaemia
                                  Reveal Solution  Discussion  0

                                  Correct Answer: B  🗳️

                                  Question #4

                                  A patient with hepatic encephalopathy is being treated with lactulose 15 mL four times daily.
                                  Over the next 72 hours, the patient becomes less agitated but remains disoriented. Which of the following should be the next step?

                                  • A. Measure stool pH to ensure that it is greater than 7.
                                  • B. Determine the frequency of bowel movements.
                                  • C. Begin branched-chain amino-acid supplementation.
                                  • D. Add neomycin 1 g four times daily.
                                  Reveal Solution  Discussion  0

                                  Correct Answer: D  🗳️

                                  Question #5

                                  A 65-year-old man presents to the internal medicine clinic with decreased exercise tolerance, lower extremity edema, and shortness of breath.
                                  He has a history of diastolic dysfunction (ejection fraction of 60%) and hypertension; BP =
                                  150/90 mm Hg, HR = 86 bpm.
                                  Current medications include digoxin 125 mcg daily, furosemide 40 mg daily, enalapril 10 mg twice daily, aspirin 325 mg daily, and potassium 10 mEq twice daily. The digoxin concentration is 0.4 ng/mL.
                                  After resolution of this exacerbation, which of the following should the pharmacotherapy specialist recommend to the internist regarding this patient's maintenance drug therapy?

                                  • A. Increase furosemide.
                                  • B. Increase digoxin.
                                  • C. Discontinue digoxin and add metoprolol.
                                  • D. Discontinue digoxin and add amlodipine.
                                  Reveal Solution  Discussion  0

                                  Correct Answer: C  🗳️

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