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BPS BPS-Pharmacotherapy Exam Syllabus Topics:

BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. An article in a clinical pharmacology journal describes a double-blind controlled trial comparing the efficacy of sumatriptan to a placebo injection for intractable migraine which used a 5 point Likert scale to evaluate headaches 2 hours after treatment. Which of the following is the most appropriate statistical test for analyzing the data?

A) Fisher's exact test
B) Student's t test
C) Chi-square test
D) Mann-Whitney U test

2. A 68-year-old female patient is admitted to the ICU for acute decompensated heart failure. She is currently intubated due to acute respiratory failure and hypoxia. After intubation, her Richmond Agitation-Sedation Scale (RASS) score is +3, and her Confusion Assessment Method for the ICU (CAM-ICU) is positive for delirium. She denies pain.
Which of the following is the best recommendation for achieving her sedation goal of RASS equals zero?

A) Administer haloperidol 5 mg intravenously q4h as needed for delirium.
B) Initiate propofol at 5 mcg/kg/min and titrate as needed.
C) Administer lorazepam infusion at a rate of 1 mg/h.
D) Initiate morphine 2 mg intravenously q6h as needed for delirium.

3. A study compared treatment with cinacalcet versus treatment with placebo in subjects with known hyperparathyroidism. The primary outcome of the study was the proportion of study subjects with a mean intact parathyroid hormone level < 250 pg/mL. Among the cinacalcet group (n = 371), 43% of subjects achieved the primary outcome; among the placebo group (n =
370), 5% achieved the primary outcome (p<0.05).
Which of the following is the number needed to treat (NNT)?

A) 8
B) 1
C) 14
D) 3

4. An investigator decides to perform a correlation analysis of the relationship between the number of cigarettes smoked per day and age. Results show a positive correlation between the two, with an r value of 0.50 and ap value for the correlation equal to 0.03. What is the most reasonable interpretation of this correlation?

A) Increased age causes students to Smoke more.
B) Increased age does not cause students to smoke more.
C) There is no relationship between age and amount of smoking.
D) There is a statistically significant numerical association between age and amount of smoking.

5. A patient with previously well-controlled diabetes is suspected to be nonadherent with medication and diet. During the patient's last visit, the pharmacy student attempt to review education materials. However, the patient said that he forgot his reading glasses and asked if he could read through the information when he got home?
Which of the following is the best course of action for the patient at his next visit?

A) Admit the patient to the hospital to optimize the diabetes regimen
B) Provider the patient with additional materials to read at home.
C) Ask the patient to read and interpret the instructions on a prescription label to evaluate literacy
D) Ask the patient to follow up with his primary care provider.

Solutions: